Toxicity Studies
|
|
Toxicity is a critical area of concern for drug candidates. Compounds may exhibit intrinsic toxicity or must undergo metabolic activation by cytochrome P450 or other enzymes to manifest toxicity.
|
Services
BD Biosciences combines itsí expertise and state-of-the-art toxicity detection technologies to help identify better drugs faster. BDís testing methods capitalize on extensive experience working with hepatocytes and recombinant cytochrome P450 enzymes. BD GentestSM Contract Research Services offer two assays for testing potential drug candidate-induced hepatotoxicity.
All tests are conducted using hepatocytes, the ìgold standardî for analyzing hepatocyte toxicity in vitro.
|
Consult the ADME Experts
Call 888.334.5229, ext. 2246, to discuss your contract needs. Customers outside the U.S. may reach us at 781.935.5115, ext. 2246. |
